Deshaun Watson threw for 194 yards and two touchdowns in less than a half and Clemson moved to 30-0 against FCS opponents with a 49-10 victory over Wofford on Saturday.
The Tigers (1-0) opened with a win for the seventh straight season, although all-Atlantic Coast Conference receiver Mike Williams left in the first quarter with a scary neck injury on a 4-yard touchdown catch.
Williams struck the goal post support and was taken to a hospital, where the school said he was standing up and had full use of all extremities.
Clemson struggled with Wofford (0-1) when the teams last met four years ago, a 35-27 victory for the Tigers.
This time, they powered past the Terriers for a 35-0 lead with five minutes left before halftime.
Wayne Gallman also had 2 touchdown runs for the Tigers.
Chase Nelson scored the only touchdown for the Terriers in the 2nd quarter right before the half.
Clemson next plays Appalachian State at home next Saturday at 12:30 pm