All lanes are now open on I-26 near mile marker 35 in Spartanburg Co.
The SC Highway Patrol says 5 vehicles were involved around 6:45 Thursday morning.
They say Daniel Lee Childers of Moore was driving westbound in his truck and hit a car parked of the shoulder of the interstate.
Childers hit a car parked on the side of the road. A tractor trailer traveling west hit the care and another tractor trailer on the side of the road.
Another tractor-trailer traveling west then hit the debris from all the accidents.
Childer is charged with driving too fast for conditions.